RUSTAMOVALONGEVITY INDEX™
Measuring how fast you are aging — through biology, not symptoms
14 Biomarkers ◆ Points-Based Scoring ◆ Biological Stress Index
A Points-Based
Biological Stress
Scoring System
The Rustamova Longevity Index™ evaluates 14 clinically validated biomarkers across 5 biological systems. Each marker receives a score from -2 (optimal) to +4 (high stress). The total stress score converts into a precise biological age — revealing how old your biology actually performs.
Strategic Biomarker Selection
Every marker was chosen for its direct, evidence-based link to biological aging velocity — inflammation, metabolism, thyroid, fatty acids, iron, and hormones.
Points-Based Scoring (-2 to +4)
Each biomarker is scored against optimal clinical ranges. Optimal markers earn negative points (age-supportive). Imbalanced markers earn positive points (biological stress).
Biological Age Conversion
Total stress score is multiplied by 0.6 to produce an age adjustment. Add that to your chronological age — that is your estimated biological age.
Inflammation
Immune & Systemic Stress
Chronic low-grade inflammation is the primary accelerator of biological aging. These three markers capture the inflammatory burden your body carries — from vascular risk to methylation stress.
Biomarker Scoring
What It Reflects
Metabolic Health
Glucose & Insulin Control
Metabolic dysregulation accelerates aging at the cellular level long before symptoms appear. This domain captures insulin sensitivity, glucose stability, and glycation stress — the engine of biological age.
Biomarker Scoring
What It Reflects
Nutrients & Fatty Acids
Cellular Building Blocks
Nutrient status and membrane composition determine cellular resilience. Vitamin D governs immune and bone signaling, while omega fatty acid balance shapes inflammation and cardiovascular flexibility.
Biomarker Scoring
What It Reflects
Thyroid Rhythm
Cellular Metabolic Pace
The thyroid sets the metabolic pace for every cell in the body. TSH reflects pituitary signaling, while Free T3 reveals how much active hormone is actually reaching your tissues.
Biomarker Scoring
What It Reflects
Iron & Hormones
Vitality & Resilience
Ferritin and DHEA-S reveal deep resilience patterns. Ferritin reflects iron storage and inflammatory status (with sex-specific optimal ranges), while DHEA-S tracks adrenal reserve and hormonal vitality.
Biomarker Scoring
What It Reflects
Beyond the 14
Biomarker Core
The points-based calculator covers 14 markers across 5 biological systems. For deep-dive clinical assessment, the full Rustamova Longevity Index™ extends into detox pathways, cardiovascular health, and the stress-cortisol axis — giving you the complete biological picture.
Detox & Methylation
- AST / ALT (liver enzymes)
- Vitamin B6, B12, Zinc, Selenium
- MMA, Folate, Full Methylation Panel
Cardiovascular
- ApoB, Lp(a)
- Creatinine, eGFR
- Full lipid particle analysis
Stress & Recovery
- Cortisol (AM)
- White Blood Cells
- Hemoglobin, Hematocrit
This is a system that measures how fast a human is aging across biology — not symptoms.
How the Index is
Calculated
A precise, reproducible points-based methodology — not guesswork. Every biomarker is clinically scored and converted into a biological age you can act on.
Enter Your 14 Biomarkers
Input your lab values for inflammation, metabolic, nutrient, thyroid, and iron/hormone markers. Sex is required for ferritin and DHEA-S scoring.
Points-Based Scoring
Each of the 14 biomarkers is scored from -2 (optimal/age-supportive) to +4 (high biological stress) based on clinical reference ranges.
Total Stress Score & Adjustment
All 14 marker scores are summed into a Total Biological Stress Score. Multiply by 0.6 to get your Biological Age Adjustment.
Biological Age & Category
Add the adjustment to your chronological age for your estimated biological age. The age gap determines your result category — Younger, Aligned, Mildly Accelerated, or Accelerated.
The Biological Age Formula
All 14 biomarker scores are summed into the Total Biological Stress Score
Scoring Legend
Every biomarker score contributes to your Total Biological Stress Score
Calculate Your
Biological Age
Enter 14 biomarkers. Get your points-based biological stress score, estimated biological age, and personalized result category — in under 5 minutes.
Developed by Dr. Rustamova ◆ 14 Biomarkers ◆ Points-Based Scoring